Abstract: The monodisperse molecularly imprinted polymer microsphere(MIPMs)for chloramphenicol was prepared by one-step seed swelling and two-step seed swelling method using linear polystyrene emulsion as seeds,methacrylic acid(MAA)as functional monomer and ethylene glycol dimethacrylate(EDMA)as crosslinker,respectively. The surface features of MIPMs were analyzed with optical microscope and SEM,and the adsorption properties of microspheres were analyzed with static adsorption experiments. The results showed that dispersion coefficient,separation factor of microspheres made by two-step seed swelling were better,the average size was 8.44 μm,dispersion coefficient was 14.2%,separation factor was 3.39.
Template and target information: chloramphenicol
Author keywords: one-step seed swelling, Two-step seed swelling, chloramphenicol, molecularly imprinted