MIPdatabase
Authors: Sellergren B, Hall AJ
Publication date: 2012
Chapter title: Molecularly Imprinted Polymers.
Page numbers: 3255-3282.
DOI: 10.1002/9780470661345.smc137 Alternative URL: http://eu.wiley.com/WileyCDA/WileyTitle/productCd-0470746408,descCd-description.html
Book title: Supramolecular Chemistry
Editors: Gale P, Steed J
Publisher: John Wiley & Sons, Ltd
ISBN: 9780470661345
Volume number: 7 (Soft Matter)
Abstract: Molecular imprinting - or templating at a molecular level - allows the preparation of synthetic polymers featuring receptor or catalytically active sites. The most common form of imprinting comprises the synthesis of reticulated polymers in the presence of templates which, widely defined, may range from ions and small molecules to biological macromolecules and ultimately microorganisms. Functional monomers act as anchors interacting with the template and holding it in place during the polymerization. Removal of the template from the formed polymer liberates binding sites complementary in shape and binding groups to the template structure. This review starts by outlining the main synthetic concepts underlying the design of imprinted polymers and thereafter highlights key contributions devoted to various molecular recognition-based applications.
Template and target information: Review - MIPs
Author keywords: molecular imprinting, imprinted polymer, MIP, template, molecular recognition, nanostructured material, plastic antibody, affinity reagent
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