MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Morihara K, Tanaka E, Takeuchi Y, Miyazaki K, Yamamoto N, Sagawa Y, Kawamoto E, Shimada T
Article Title: Footprint catalysis .3. Inducible alteration of substrate specificities of silica(alumina) gel catalysts for 2,4-dinitrophenolysis of toluic anhydrides by footprint imprinting.
Publication date: 1989
Journal: Bulletin of the Chemical Society of Japan
Volume: 62
Issue: (2)
Page numbers: 499-505.
DOI: 10.1246/bcsj.62.499

Abstract: A tailor-made catalyst design was attempted for a required substrate specificity by the authors' footprint imprinting method. Two silica(alumina) footprint catalysts were prepared by imprinting with N-benzoylbenzenesulfonamide (1) and N-(p-toluoyl)-p-toluenesulfonamide (2) from the same aluminum ion-doped silica gel. Their catalytic effects upon 2,4-dinitrophenolysis of benzoic anhydride, p-, m-, and o-toluic anhydrides were compared in order to find any difference in substrate specificities. The catalyst prepared by imprinting with 1 showed the largest specificity(kcat/Km) toward benzoic anhydride, whereas the catalyst prepared with 2 showed the largest specificity toward p-toluic anhydride. This finding evidently demonstrated that the substrate specificities of footprint catalytic sites are alterable, as required through selecting appropriate transition state analogs as template molecules for footprint marking.


  I love MISPE shirt  multi MIPs logo mug  British periodic table patriotic tote bag

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner