MIPdatabase
Authors: Zhou Q, Liu L, Zhai HY, Zhu MF, Zhang ZY
Article Title: Electrochemical behavior and determination of paracetamol at molecular imprinted film modified glassy carbon electrode.
Publication date: 2012
Journal: Journal of Instrumental Analysis
Volume: 31
Issue: (5)
Page numbers: 589-592.
Alternative URL: http://fxcsxb.com/ch/reader/view_abstract.aspx?file_no=20120515&flag=1
Abstract: Using paracetamol(PCT) as template and methylacrylic acid as functional monomer, a molecular imprinted polymer film was synthesized on the surface of glassy carbon electrode(GCE) through in-situ polymerization by UV irradiation.After the template was removed with methanol and formic acid mixture solution, a paracetamol imprinted polymer film modified glassy carbon electrode(MIP-GCE) was prepared, and a method for the determination of PCT was developed with MIP-GCE.The sensor exhibited a good selectivity and sensitivity.The calibration curve was linear in the range of 5.0×10-5-1.0×10-3 mol L-1 with a detection limit of 1.4×10-6 mol L-1.The method was applied in the determination of PCT in drugs, with recoveries of 96%-105%.
Template and target information: paracetamol, PCT, acetaminophen
Author keywords: paracetamol, molecular imprinted film, Glassy carbon electrode, electrochemistry, in-situ polymerization, UV irradiation
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