MIPs logo MIPdatabase      MIP2018 Conference website
Custom Search
Reference type: Journal
Authors: Shi XZ, Song SQ, Sun AL, Liu JH, Li DX, Chen J
Article Title: Characterisation and application of molecularly imprinted polymers for group-selective recognition of antibiotics in food samples.
Publication date: 2012
Journal: Analyst
Volume: 137
Issue: (14)
Page numbers: 3381-3389.
DOI: 10.1039/C2AN35213C

Abstract: Group-selective molecularly imprinted polymers (MIPs) for amphenicol antibiotics, including chloramphenicol (CAP), thiamphenicol (TAP), florfenicol (FF), and florfenicol amine (FFA), were developed for the first time using TAP as the template molecule. The characteristics of the obtained MIPs were systematically evaluated by chromatographic methods and frontal analysis, demonstrating that the MIPs had excellent chromatographic behaviors, good selectivity, and high-binding capability. A molecularly imprinted solid-phase extraction (MISPE) procedure was developed based on the chromatography results. The MIPs exhibited better group selectivity for CAP, TAP, FF, and FFA than non-imprinted polymers (NIPs) under the optimized washing conditions of 10% acetonitrile in PBS buffer (25 mmol L-1, pH = 5). Compared with conventional solid-phase extraction, significant recoveries ranging from 92.4% to 98.8% with lower relative standard deviation values in the range of 3.2-7.3% for both intraday- and interday-assays were obtained. The limits of detection (LODs) of MISPE for CAP, TAP, FF, and FFA in shrimp were found to be 0.016, 0.093, 0.102, and 0.029 μg kg-1, respectively. The results acquired in this study contribute to the strategic development of MIPs and MISPE methods for the multi-residual recognition of antibiotics from complex matrices
Template and target information: amphenicol antibiotics, chloramphenicol, CAP, thiamphenicol, TAP, florfenicol, FF, florfenicol amine, FFA


  Template of Doom spoof movie poster mug  Chemistry peptide mug  Chemists are fun customisable shirt

Molecules Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon