Book title: Molecularly Imprinted Sensors
Editors: Li SJ, Ge Y, Piletsky SA, Lunec J
Publisher: Elsevier
City: Amsterdam
ISBN: 978-0-444-56331-6
Abstract: Over the last few years molecular imprinting has proven itself one of the finest techniques for designing synthetic materials of a wide range of applications. The most remarkable aspect of these materials is in crafting chemical-sensitive coatings. Molecular recognition of analyte is accomplished by the imprinted surface following the concept of host guest interaction. Noncovalent forces play a vital role in the binding of analyte with imprinted polymers, and therefore, they are equally important for providing selectivity to analytes having the least functionality. High mechanical stability, tunable layer thickness, and reversible binding with analyte species makes them ideal for coupling with suitable transducers, thus ultimately developing modern chemical sensors. In this regard, the selection of transducer depends mainly on molecular imprinted polymer and characteristic properties of analyte, consequently producing optical and mass-sensitive sensors. These detection techniques have inherent advantages providing low detection limits, prompt response, and suitable dynamic range, which makes their use optimal in sensor development. This chapter deals with all the issues concerning molecular imprinted polymers as sensitive coating material and focuses on their comparative optical and mass-sensitive sensing applications
Template and target information: Review - MIP sensors with optical and mass-sensitive detection