Paper 8185

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Reference type: Journal
Authors: Kryscio DR, Fleming MQ, Peppas NA
Article Title: Protein Conformational Studies for Macromolecularly Imprinted Polymers.
Publication date: 2012
Journal: Macromolecular Bioscience
Volume: 12
Issue: (8)
Page numbers: 1137-1144.
DOI: 10.1002/mabi.201200068

Abstract: CD is used to clearly show the negative impact of common ligands on the overall conformation of BSA, a typical protein template in macromolecularly imprinted polymers. This change occurs at concentrations far lower than those generally used in the literature. These findings are important as they offer insight into a potential fundamental reason for the lack of success in protein imprinting to date despite significant interest from the scientific community
Template and target information: protein, BSA, bovine serum albumin
Author keywords: Bovine serum albumin, circular dichroism, molecular imprinting, protein conformation, protein imprinted polymers

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