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Reference type: Journal
Authors: Tang ML, Zhang J, Zhuang SL, Liu WP
Article Title: Development of chiral stationary phases for high-performance liquid chromatographic separation.
Publication date: 2012
Journal: TrAC Trends in Analytical Chemistry
Volume: 39
Page numbers: 180-194.
DOI: 10.1016/j.trac.2012.07.006
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0165993612002002

Abstract: Chromatography technology based on chiral stationary phases (CSPs) for enantioseparation is widely used for resolution and preparation of biochemicals (e.g., drugs, foods, fragrances and pollutants). In this review, we focus on the development of CSPs for high-performance liquid chromatography (HPLC), including the recognition mechanism, applications and limitations of classical CSPs, newly discovered types of CSP, and also the methods for the rational design of future CSPs on the basis of computational chemistry
Template and target information: Review - chiral chromatography
Author keywords: Biochemical, Chiral stationary phase (CSP), chromatography, Computational chemistry, enantioseparation, High-performance liquid chromatography (HPLC), Preparation, Recognition, rational design, resolution


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