MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Denizli A
Article Title: Plasma fractionation: conventional and chromatographic methods for albumin purification.
Publication date: 2011
Journal: Hacettepe Journal of Biology and Chemistry
Volume: 39
Issue: (4)
Page numbers: 315-341.
Alternative URL: http://www.hjbc.hacettepe.edu.tr/journal/volume-39/issue-4/39_4_315-341.pdf

Abstract: Plasma fractionation is the first process for large scale protein purification developed about 60 years ago by Cohn and co-workers. Currently therapeutically important proteins are human serum albumin (HSA), immunoglobulin G (IgG), coagulation factor VIII and protease inhibitors. HSA is one of the most abundant proteins in plasma and, together with IgGs, constitutes 80% of all plasma proteins. According to the data, HSA represented approximately 50% of all sales of therapeutic plasma protein products. The purification of HSA is generally required for the treatment of hypoproteinemia and heavy loss of blood, requires relatively high purity for medical use. HSA also used for therapeutic purposes such as shock, burns, hypoalbuminemia, surgery, trauma, cardiopulmonary bypass, the acute respiratory distress syndrome, hemodialysis, acute nephrosis, hyperbilirubinemia, acute liver failure, acites, and sequestration of protein-rich fluids in acute peritonitis, pancreatitis, mediastinitis and extensive cellulites.
Template and target information: Review - plasma fractionation
Author keywords: albumin, lasma fractionation, ffinity chromatography, lasma proteins

  Periodic table Prof shirt  Mug featuring the name Adil spelled out in the single letter amino acid code  Gravity waves shirt


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner