Authors: Nicholls IA
, Matsui J
, Krook M
, Mosbach K
Some recent developments in the preparation of novel recognition systems: A recognition site for the selective catalysis of an aldol condensation using molecular imprinting and specific affinity motifs for a-chymotrypsin using a phage display peptide library.
Publication date: 1996
Journal: Journal of Molecular Recognition
Abstract: Molecular imprinting and phage display library technologies are rapidly being accepted as useful techniques for the generation of ligand-selective recognition motifs. The use of molecular imprinting to produce a novel type II aldolase mimic selective for the cobalt(LT)-mediated aldol condensation of benzophenone and acetaldehyde is reported here, Furthermore, peptide motifs have been identified which are acting as 'affinity ligands' selective for the recognition of the enzyme alpha-chymotrypsin using phage display techniques
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