Alternatively for mipdatabase quick searches go here

Custom Search

Abstract: A novel flow injection chemiluminescence (FI-CL) sensor for the determination of sulfamethoxazole (SMZ) was established which using chitosan/graphene oxide-molecularly imprinted polymers (CG-MIP) as recognition element. The SMZ-CG-MIP was synthesized in acetone as solvent and chitosan/graphene oxide for support, using acrylamide as functional monomer, ethylene glycol dimethacrylate as cross-linker and 2,2-azobisisobutyronitrile as initiator. The CG-MIP showed satisfactory recognition capacity for the SMZ. Then the synthesized CG-MIP was employed as recognition by packing into a lab-made tube connected in FI-CL analyzer to establish a novel CL sensor respectively. The CL intensity responded linearly to the concentration of SMZ in the range 1.0 x 10-7 mol/L to 2.3 x 10-3 mol/L with a detection limit of 2.9 x 10-8 mol/L (3σ), which is lower. The relative standard deviation for the determination of 4.0 x 10-4 mol/L of SMZ was 1.92% (n = 11). The sensor is reusable and has a great improvement in sensitivity and selectivity for CL analysis which applied to the determination of SMZ in drug samples
Template and target information: sulfamethoxazole, SMZ
Author keywords: Flow injection chemiluminescence, chitosan, Graphene oxide, Molecularly imprinted polymers, sulfamethoxazole