MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Qiu HM, Fan LL, Li XJ, Li LL, Sun M, Luo CN
Article Title: A microflow chemiluminescence sensor for indirect determination of dibutyl phthalate by hydrolyzing based on biological recognition materials.
Publication date: 2013
Journal: Journal of Pharmaceutical and Biomedical Analysis
Volume: 75
Page numbers: 123-129.
DOI: 10.1016/j.jpba.2012.11.010
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0731708512006152

Abstract: A microflow chemiluminescence (CL) sensor for determination of dibutyl phthalate (DBP) based on magnetic molecularly imprinted polymer (MMIP) as recognition element was fabricated. Briefly, a hydrophilic molecularly imprinted polymer layer was produced at the surface of Fe3O4@SiO2 magnetic nanoparticles (MNPs) via combination of molecular imprinting and reversible stimuli responsive hydrogel. In this protocol, the initial step involved co-precipitation of Fe2+ and Fe3+ in an ammonia solution. Silica was then coated on the Fe3O4 nanoparticles using a sol-gel method to obtain silica shell magnetic nanoparticles. The MMIP was synthesized using methacrylic acid (MAA) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as cross-linker and 2, 2-azobisisobutyronitrile (AIBN) as initiator in chloroform. Then the synthesized MMIP and magnetic non-molecular imprinted polymers (MNIP) were employed as recognition by packing into lab-made straight shape tubes, connected in CL analyzer for establishing the novel sensor with a single channel syringe pump. And a mixer for hydrolyzing of DBP was followed. Based on this experiment principle, DBP was determined indirectly. And the MMIP showed satisfactory recognition capacity to DBP, resulting to the wide linear range of 3.84 x 10-8 to 2.08 x 10-5 M and the low detection limit of 2.09 x 10-9 M (3σ) for DBP. The relative standard deviation (RSD) for DBP (3.20 x 10-6 M) was 1.40% (n = 11). Besides improving sensitivity and selectivity, the sensor was reusable. The proposed DBP-MMIP-CL sensor has been successfully applied to determine DBP in drink samples
Template and target information: dibutyl phthalate, DBP
Author keywords: Microflow chemiluminescence, Dibutyl phthalate, Magnetic molecularly imprinted polymer, Hydrolyzing


  Eat, sleep, imprint, repeat shirt  SMI logo mug  Man of proper-tea mug

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner