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Abstract: Molecularly imprinted polymers (MIPs) particles prepared by molecular imprinting technique (MIT) possess the ability of specific identification and selective affinity towards template molecules and their structural analogues, they also have a large specific surface area and rapid mass transfer kinetics, thus they have been widely used as stationary phases in liquid chromatography and matrixes in solid phase extraction. Using molecularly imprinted particles as capillary electrochromatography (CEC) stationary phase, which combines the high speed and efficiency of CEC with the high affinity and selectivity of MIPs, has become one of the most promising separation technique in analytical science. There are several different strategies of molecularly imprinted particles applied in CEC: as packing material packed into the capillary column; as entrapping material entrapped into different matrix frameworks inside the capillary column; as pseudostationary phases (PSPs) added into the running buffer of CEC. This review focuses on the recent developments of MIPs particles in CEC and prospects the future development in this field.
Template and target information: Review - MIPs in CEC
Author keywords: molecularly imprinted polymer (MIP) particles, capillary electrochromatography (CEC), stationary phases, review