Abstract: An electrochemical bionic sensor for cholesterol detection is developed with molecular imprinting self-assembled film deposited on the screen printed gold electrode. The surface topography of planar bare gold electrode and thick film bare gold electrode are compared with Scanning Electron Microscope (SEM). The electrochemical characteristics of the electrode during modification are studied with cyclic voltammetry technique. The results show that thick film electrode by screen printing technology is suited to the modification of molecular imprinting self-assembled film, and exhibits obvious amplification at nano level. The response of the sensor to the concentration of cholesterol is detected with chronoamperometric measurements. Cholesterol between 0 and 700 nM are detected with this sensor. The linearity range is from 50 nM to 700 nM with the sensitivity of -4.94 μA/[lg(nM)] and linearly dependent coefficient of 0.994. And this cholesterol sensor has high accuracy, which reaches 99.56%.
Template and target information: cholesterol
Author keywords: Electrochemical sensor, molecular imprinting, SAM, cholesterol, Screen printing