Abstract: A series of chitosan containing crosslinkable functional groups were synthesized from chitosan (CS) and glycidyl methacrylate (GMA). FTIR and XRD were applied to characterize the structure and properties. It was found that the synthesized products (CS-GMA) is easily soluble in water and polar aprotic solvent. As containing artificial recognition sites for guanine, it has been polymerized as the functional monomer under ammonium persulphate as the initiator and ethylene glycol dimethacrylate (EGDMA) as the cross-linker leading to the molecularly imprinted polymer (MIP). The sorption of the MIP was via the static adsorption and the determination of guanine was carried out by ultraviolet spectrophotometry. The resulting guanine-imprinted MIP exhibites a much higher imprinting effect for guanine than for a structural analogue, adenine.
Template and target information: guanine
Author keywords: chitosan, glycidyl methacrylate, molecularly imprinted polymer, Guanine