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Abstract: Sample preparation is still considered the bottleneck of the whole analytical process. In this regard, improvement in selectivity during extraction and/or subsequent clean-up of sample extracts is an area of intense research activity. One of the most versatile, promising options is to incorporate molecularly-imprinted polymers (MIPs) into sample preparation. MIPs are tailor-made, stable polymers with molecular recognition abilities, so that they are excellent materials for providing selectivity in sample preparation. This review describes the use of MIPs in sample preparation, including solid-phase extraction, and corresponding recent improvements, and their recent incorporation into other extraction techniques (e.g., solid-phase microextraction, matrix-solid phase dispersion and stir-bar sorptive extraction). It discusses the advantages and the drawbacks of each methodology, and the future expected trends
Template and target information: Review - MIPs in sample preparation
Author keywords: extraction, Matrix solid-phase dispersion (MSPD), Molecularly-imprinted polymer (MIP), molecular recognition, Sample clean-up, sample preparation, selectivity, Solid-Phase Extraction (SPE), Solid-phase microextraction (SPME), Stir-bar sorptive extraction (SBSE)