MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Pande VS, Grosberg AY, Tanaka T
Article Title: How to create polymers with protein-like capabilities: A theoretical suggestion.
Publication date: 1997
Journal: Physica D
Volume: 107
Issue: (2-4)
Page numbers: 316-321.
DOI: 10.1016/S0167-2789(97)00099-7

Abstract: The synthesis of a man-made polymer capable of functioning in a protein-like fashion can be of tremendous technological importance, and may also shed light on the natural creation of the molecular basis of life, In case of proteins, the unique 3D fold, responsible for the particular functionality of the molecule, is determined by the particular sequence of monomer units. We suggest a procedure, which we call imprinting, to control the monomer sequence of an artificial heteropolymer during its synthesis in order to obtain a heteropolymer with the protein-like properties of quick and reliable renaturability to some unique fold capable of certain functional properties. To control the sequence formation, our procedure employs interactions between monomers. We will show that this leads to renaturable chains, because renaturation is governed exactly by the same interactions between monomer units. We present here both analytical and computational study of imprinting, yielding the requirements on the set of monomers chosen and further more specific prescriptions for the experimental verification of this theory


  Periodic table Stew - the chemical formula for stew shirt  Periodic table Bag bag  Meerkat somebody mention coffee mug

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner