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Abstract: Displacement reactions are very popular in nature, ranging from texbook knowledge of the Zn-CuSO4 system to modern functional nucleic acid-involved metal ion displacement. Though synthetic chemistry harvests a lot from displacement reactions, analytical chemistry benefits greatly from various displacement reaction strategies, such as sensitivity improvement. In particular, the use of indicator displacement assay for new sensor development is of great interest worldwide. In this review, we summarize the advances in utilization of displacement reactions for improved spectrometric analysis. The main contents include displacement-based preconcentration schemes for trace metal analysis by analytical atomic spectrometry, indicator displacement assays focusing on the use of advanced nanomaterials, and displacement immunoassays using spectrometric measurements, with 117 references
Template and target information: Review - assays for spectrometric analysis
Author keywords: displacement sorption, preconcentration, indicator displacement assay, Sensor array, displacement immunoassay, spectrometry