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Reference type: Conference Proceeding
Authors: Xu CM, Li ZW, Liu L
Publication date: 2013
Article title: Chiral Separation of R,S 3-(4-Fluorophenyl) -2,2-Dimethylcyclopane Carboxamide with Monolithic Molecularly Imprinted Polymers.
Page numbers: 40-43
DOI: 10.4028/www.scientific.net/AMR.706-708.40 Alternative URL: http://www.scientific.net/AMR.706-708.40

Proceedings title: Advanced Materials Research
Editors: Chen R, Sung WP, Kao JCM
Publisher: Trans Tech Publications
City: Switzerland
Volume number: 706-708
Conference information: Mechatronics and Intelligent Materials III

Abstract: A monolithic column of molecularly imprinted polymer was prepared by an in situ polymerization method with a new compound R, S 3-(4-Fluorophenyl) -2, 2-Dimethylcyclopane Carboxamide which has fluorin organic compound as the template. The molecular recognition capabilities of the prepared monolithic MIP were evaluated by separating the enantiomers. The characteristics of the column and the influences of mobile phases were studied. The results showed that the monolithic column has chiral recognition capability for the template and the enantiomers were baseline separated even in aqueous solution.
Template and target information: R,S 3-(4-Fluorophenyl) -2, 2-Dimethylcyclopane Carboxamide, (4-Fluorophenyl) -2, 2-Dimethylcyclopane Carboxamide
Author keywords: chiral separation, Molecularly imprinted polymers, monolithic column


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