Abstract: We describe a molecularly imprinted electrochemical sensor for selective and sensitive determination of β2-agonists. It is making use of a combination of single-wall carbon nanotubes (SWNTs) with a molecularly imprinted sol-gel. The SWNTs were introduced in order to enhance electron transport and sensitivity. The imprinted sol-gel film with its specific binding sites acts as a selective recognition element and as a preconcentrator for β2-agonists. The morphology of the imprinted film was characterized by scanning electron microscopy. The optimized sensor displays high sensitivity and excellent selectivity for the β2-agonists as shown for their determination in human serum samples
Template and target information: β2-agonists, Salbutamol, clenbuterol, terbutaline, Metaproterenol, Fenoterol, Cimbuterol, Mabuterol, Isoxsuprine, Brombuterol, Ractopamine, Ritodrine hydrochloride
Author keywords: molecularly imprinted polymer, Single-wall carbon nanotubes, sol-gel, β2-Agonists