MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Mou XL, Zhang WP, Chen ZL
Article Title: Highly selective extraction of baicalin in natural herbs and medicinal preparations by molecularly imprinted polymer.
Publication date: 2013
Journal: Journal of Applied Polymer Science
Volume: 130
Issue: (3)
Page numbers: 1873-1878.
DOI: 10.1002/app.39410

Abstract: Selective extraction of bioactive compounds in natural products and traditional medicines is difficult but necessary for drug analysis and new drug development. In this study, baicalin-imprinted polymer particles were prepared for selective recognition and extraction of baicalin from herbs and traditional Chinese medicines. The molecularly imprinted polymer (MIP) was synthesized by co-polymerization of 4-vinylpridine and ethylene glycol dimethacrylate in the presence of baicalin with a ratio of 8 : 40 : 1, where N,N-dimethyl formamide/acetonitrile served as porogen. The prepared MIP particles showed good selectivity by comparing with non-imprinted polymer and possessed an imprinted factor of 2.17; selectivity to other molecules was also tested by extracting an analogue, naringin. The performances of the MIP particles were systematically investigated, including adsorption kinetics, isotherm experiment, and Scatchard analysis. The imprinted particles were also applied to extract baicalin from natural herb Plantago asiatica L, and traditional Chinese medicine Longdanxiegan bolus. The results showed that baicalin in these complex matrixes could be selectively extracted and well isolated with other components. -« 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 1873Gă˘1878, 2013
Template and target information: baicalin
Author keywords: adsorption, applications, Biomedical applications


  SMI logo lapel pin  Mother Periodic table shirt  Lab Chick script shirt

Molecules Special Issue call      Appeal for information






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon