Abstract: In recent years, the development of new, attractive applications of imprinted materials have enabled an advance in molecular imprinting technology. New methodologies have been implemented on the basic technology and increasing efforts are being made to widen the horizon. In addition to further developments in the separation sciences. imprinted materials have increasingly been used as recognition elements in immunoassay-type analyses. in biosensor-like devices and in catalytic applications. This presentation will point to some recent developments in the use of imprinted materials obtained by self-assembly using only non-covalent interactions. In particular, the use of such materials in aqueous media in radio-immunoassays and as auxiliary agents in enzymatic syntheses will he discussed. 1. Mosbach, K. and Ramström, O. 1996. The emerging technique of molecular imprinting and its future impact on biotechnology. Bio/Technology 14, 163. 2. Ramström. O., Ye, L. and Mosbach, K. 1996. Artificial antibodies to corticosteroids prepared by molecular imprinting. Chem. Biol. 3, 471