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Reference type: Journal
Authors: Rashid BA, Briggs RJ, Hay JN, Stevenson D
Article Title: Preliminary evaluation of a molecular imprinted polymer for solid-phase extraction of tamoxifen.
Publication date: 1997
Journal: Analytical Communications
Volume: 34
Issue: (10)
Page numbers: 303-305.
DOI: 10.1039/a705884e

Abstract: A molecular imprinted polymer, prepared around a tamoxifen template, has been synthesised. The feasibility of using this polymer for solid-phase extraction of tamoxifen from biological samples has been investigated. The results show that the drug can be quantitatively retained and eluted from the polymer using acetonitrile-acetic acid. Experiments with biological fluids indicate that clean traces are obtained for HPLC with UV detection using this type of protocol


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