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Reference type: Journal
Authors: Alvarez-Lorenzo C, Concheiro A
Article Title: Bioinspired drug delivery systems.
Publication date: 2013
Journal: Current Opinion in Biotechnology
Volume: 24
Issue: (6)
Page numbers: 1167-1173.
DOI: 10.1016/j.copbio.2013.02.013
Alternative URL: http://www.sciencedirect.com/science/article/pii/S095816691300027X

Abstract: The way Nature designs, processes and assembles molecular building blocks to fabricate high performance materials with a minimum of resources is a suitable model for the design of drug delivery systems (DDS) with advanced functionalities. Bioinspired preparation methods that involve the use of superhydrophobic surfaces, layer-by-layer assembly or protein-driven growth are being successfully implemented to create a wide range of polymeric and hybrid structures. Mimicking the surface, shape, texture and movement of cells and microorganisms help to overcome phagocytosis and attain efficient targeting of the drug carriers, while transposition of the feed-back regulation mechanisms and the functions of membrane channels and physiological receptors may notably enhance the spatiotemporal control of drug release. These aspects are addressed in the present review
Template and target information: Review - drug delivery systems


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