Inventors: Komiyama M
, Asanuma H
, Kakazu M
Method for synthesizing crosslinked cyclodextrin polymer and removal of cholesterol with the polymer
Publication date: 1998
PROBLEM TO BE SOLVED: To obtain a material which has improved adsorptivity for a substrate and can adsorptively remove cholesterol by crosslinking cyclodextrin in the presence of a template molecule and removing the template molecule from the crosslinked cyclodextrin.
SOLUTION: An aqueous solution containing alpha -, beta -, gamma - or delta -cyclodextrin is mixed with a solution prepared by dissolving a template molecule in an organic solvent being inert to isocyanato groups and being capable of dissolving a crosslinking agent to obtain a dextrin/temperate molecule clathrate complex. This complex is reacted with a crosslinking agent to crosslink the cyclodextrin and washed with an organic solvent such as acetone, tetrahydrofuran or 1,4- dioxane to remove the template molecule and to obtain a crosslinked cyclodextrin polymer. This polymer is added to a solution containing cholesterol under agitation to selectively adsorb cholesterol. The polymer containing the adsorbed cholesterol is regenerated by treatment with a good solvent for cholesterol.
Join the Society for Molecular Imprinting
New items RSS feed
View latest updates
Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent
to go to the sign-up page.
Is your name elemental
? Enter your name and find out by clicking either of the buttons below!
Other products you may like: