Inventors: Okamoto Y
, Nakano T
Synthesis of optically active crosslinked gel
Publication date: 2000
PROBLEM TO BE SOLVED: To obtain an optically active crosslinked gel having stability to solvolysis and capable of being expected to have excellent optical properties by employing an optically active polymer as a mold.
SOLUTION: The objective crosslinked gel is obtained by polymerizing a monomer such as a bifunctional monomer (e.g. divinylbenzene or the like) and a monofunctional monomer (e.g. methacrylic acid or the like) in a solvent such as tetrahydrofuran and chloroform in the presence of an initiator (e.g. 2,2'- azobisisobutyronitrile or the like) and an optically active polymer such as an optically active (meth)acrylate polymer (e.g. triphenylmethyl methacrylate or the like) having a repeating unit of formula I or II [wherein, R1-R3 are each a group expressed by formula III (wherein, X is an alkyl or the like; (n) is 0-7), a cyclic alkyl or the like] as a template, and then by removing the template polymer from a resultant product. As the crosslinked gel has chiral holes, it has asymmetric distinction capacity and is useful as an optical resolution agent for various racemic modifications.
Join the Society for Molecular Imprinting
New items RSS feed
View latest updates
Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent
to go to the sign-up page.
Is your name elemental
? Enter your name and find out by clicking either of the buttons below!
Other products you may like: