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Inventors: Haginaka A, Sanpei H
Patent Title: Separating agent, separation of estrogen compound and estrogenic substance, and screening, adsorbing and removing of estrogenic substance
Publication date: 2000
Publication number: JP2000135435

Abstract: PROBLEM TO BE SOLVED: To separate estrogen compounds and estrogenic substances by reverse phase high-performance liquid chromatography by introducing a template structure to the estrogen compounds and estrogenic substances into polymer particles. SOLUTION: Estrogen compounds and/or estrogenic substances are mixed with a polymerizable monomer this monomer is polymerized and the estrogen compounds and/or estrogenic substances are removed to introduce a template structure into polymer particles. In other way, estrogen compounds and/or estrogenic substances are mixed with a linear polymer, this polymer is allowed to react with a crosslinker to form a crosslinked polymer and the estrogen compounds and/or estrogenic substances are removed. The polymer particles may be produced by seed polymerization. When the polymerizable monomer is polymerized, a multifunctional polymerizable monomer is preferably used to form a crosslinked structure.
URL: http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=JP2000135435&F=0

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