Inventors: Mosbach K, Nicholls IA, Ramström O
Patent Title: Use of molecularly imprinted polymers for stereo- and/or regioselective synthesis
Publication date: 2005
Publication number: US2005_0027102

Abstract: Molecularly imprinted polymers can be utilized in stereo- and regio-selective synthesis. These systems can be utilized, e.g. for peptide synthesis, by selectively coordinating reactants at a predetermined preformed cavity. Further, such polymers may be used for the selective removal of one enantiomeric species from solution, allowing reaction to be directed to another species in bulk solution leading to stereoselective and/or regio-selective synthesis in the cavity of for instance peptides. Additionally, when utilized as regioselectively interacting protectioning matrices, these polymers can direct reaction to an alternate centre of a reacting substrate.
URL: http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=US2005027102&F=0