Inventors: Darling GD
, Heisler S
, Stranix BR
, Turkewitsch P
, Wandelt B
Nanoparticles imprinted with recognition sites for target molecules
Publication date: 1996
The present invention provides solid imprinted particles comprising recognition sites spaced on the surface thereof which selectively bind a preselected template compound (T), wherein said recognition sites are each defined by a shaped polymeric matrix conforming to the shape and size of T, comprising a unit of the formula -B-Det, wherein B is bound to the polymeric matrix and also comprises a functional group which reversibly binds to T, and Det is a moiety capable of generating a detectable signal which changes following binding of B to template compound T.
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