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Inventors: Afeyan NB, Varady L, Regnier FE
Patent Title: Molecular imaging method
Publication date: 1993
Publication number: WO9319844

Abstract: Disclosed are chemically-produced specific binding, "molecular imaged" sorbents which reversibly bind a preselected macromolecule by spacially matched multipoint interactions between functional groups synthesized on the surface of the sorbent and functional groups on the surface of the macromolecule. Also disclosed are methods of producing such sorbents. The sorbents typically are high surface area solids comprising surface binding regions which have charged-groups, metal coordinating groups, hydrophobic moieties, or various combinations thereof anchored thereto and spaced in the mirror image of complementary interactive groups on a surface of the macromolecule.
URL: http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=WO9319844&F=0

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