Inventors: Piletsky SA
, Piletska OV
, Karim K
, Legge CH
, Subrahmanyam S
Rationally designed selective binding polymers
Publication date: 2006
A polymer able to bind a target compound selectively is designed by producing a virtual library of polymerisable monomers, and molecular models of the target compound and one or more potential interferents. The library is screened to identify monomers with substantial differences in strengths of binding to (a) target and (b) interferent. Monomers favouring the target may be used to produce polymers for selectively binding the target, for use in separation or analytical processes.
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