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Inventors: Constantino P
Patent Title: Lipopolysaccharide decontamination
Publication date: 2009
Publication number: WO/2009/087571

Abstract: Materials and methods for the selective removal of lipopolysaccharide during the purification of molecules of biopharmaceutical interest are based on a polymeric substrate that binds lipopolysaccharide. Preferably, the polymeric substrate is selective for at least one of heptose and 2-keto-3-deoxyoctonic acid. The substrate can be formed by a process comprising: (i) contacting a homogeneous polymer solution and a template solution; (ii) carrying out a phase inversion of the resulting solution; and (iii) removing the template.
URL: http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_gb&FT=D&date=20090716&CC=WO&NR=2009087571A2&KC=A2

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