Inventors: Piletska O,
Piletsky S,
Coker R
Patent Title: Modified cartridge with adsorbent polymer for solid-phase extraction (SPE)
Publication date: 2009
Publication number: WO/2009/098522
Abstract: A solid phase extraction (SPE) cartridge for use in a fluorimetric assay comprises an elongate container (10) of a material permeable to fluorescent radiation, having an open inlet end and an open outlet end. For assay of a compound of interest, a solid adsorbent stationary phase (11) is provided in the container to adsorb the target compound from a mobile phase. To reduce background fluorescence that may interfere with the assay, at least one region (12,13) that is is at leastpartially impermeable to fluorescent radiation, for example by absorbence, scattering or refracting, is provided in or on the container wall, suitably on the outlet side and/or the inlet side of the anticipated location of a band or layer (14) of a compound of interest adsorbed in the stationary phase during an SPE procedure.
URL: http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_gb&FT=D&date=20090813&CC=WO&NR=2009098522A1&KC=A1
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