Inventors: Ding L, Chen LG, Zhang XP, Xu Y, Jin HY
Patent Title: Preparation of magnetic molecularly imprinted polymer and application in complex sample pre-processing
Publication date: 2009
Publication number: CN101550207

Abstract: The present invention specifically adopts a simple method for preparing a molecularly imprinted polymer and directly applies the molecularly imprinted polymer to the extraction separation of trace substance in the complex sample pre-processing. The invention adopts a chemical coprecipitation method for preparing Fe3O4 magnetofluid. Then the surface of Fe3O4 magnetofluid is modified with oleic acid. The template molecules and functional monomers are realized with preassembling and are mixed with the cross linker and modified magnetofluid. Then the mixture is added into the polymer solvent containing dispersing agent. After the reaction is finished, magnetic field separation is executed. The polymer is dried after eluting the formwork molecules. A three-phase extraction system which is established on the base of magnetic molecularly imprinted polymer can be directly applied to the extraction separation of complex samples of food, environment and biological sample. The method of the invention has excellent selectivity and can eliminate the matrix interference in the sample. Furthermore as the polymer has excellent magnetism, the polymer can excellently realize the separation to the sample matrix after the extraction, and the polymer has broad application prospect in the complex sample pre-processing.
URL: http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20091007&CC=CN&NR=101550207A&KC=A