Inventors: Huang JD, Pei MS, Yu JH, Wang SH, Zhu H, Zhang XM, Lin Q, He XR, Ge SG, Sun NX, Yuan L
Patent Title: Glycosyl-functionalization bacterial toxin molecularly imprinted polymer, preparation method and application
Publication date: 2009
Publication number: CN101555289

Abstract: The invention relates to a glycosyl-functionalization bacterial toxin molecularly imprinted polymer and a preparation method thereof. The glycosyl-functionalization bacterial toxin molecularly imprinted polymer is prepared by mixing 0.01-10molof bacterial toxin template molecule, 1mol of functional monomer, 0.5-8mol of cross linker, 30-65molof pore-foaming agent and 0.05-0.20mol of evocating agent and carrying out in-situ polymerization. The invention also discloses the application of a glucide compound as a functional monomer in preparing the bacterial toxin molecularly imprinted polymer. The glycosyl-functionalization bacterial toxin molecularly imprinted polymer provided by the invention combines the special distinguishing mechanism of glucid and bacterial toxin and the special distinguishing mechanism of molecularly imprinted polymer to the bacterial toxin, thereby having favorable molecular distinguishing performance and greatly improving the sensitivity and selectivity for the detecting bacterial toxin.
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