Inventors: Li L, Li WL, Ding HY
Patent Title: Propofol molecularly imprinted polymer, preparation method and use thereof
Publication date: 2009
Publication number: CN101386664

Abstract: The invention relates to the technical field of sample preliminary treatment in the pharmaceutical analysis, in particular to a propofol molecular engram polymer and propofol molecular engram solid phase extraction column and a preparation method and application thereof. The functional monomer of the molecular engram polymer is methacrylic acid, a cross-linking agent is ethylene glycol dimethacrylate, and an engram molecule is propofol. The propofol molecular engram polymer is used to prepare the propofol molecular engram solid phase extraction column. The propofol molecular engram solid phase extraction column is used to separate a biological sample enriched with the propofol. The propofol molecular engram polymer can be used as a filler of the solid phase extraction column and a chromatographic column to separate the propofol in the enriched complex biological sample with high selectivity. Compared with the prior solvent extraction method and a C18 solid phase extraction method, the propofol molecular engram solid phase extraction column is simpler, faster and more efficient.
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