Inventors: Chen LX, Wang LY, Wang X, He XW, Zhang YK, Wang YF
Patent Title: Sulfalene oxazole molecular engram polymer producing method
Publication date: 2008
Publication number: CN101245121

Abstract: The invention relates to a method for preparing molecularly imprinted sulfamethoxazole polymer with ionic liquid to be a pore-forming agent. The specific steps are as follows: functional monomers and template molecules are dissolved into the ionic liquid and crosslinker and initiator are added after oscillation. Nitrogen is added to eliminate oxygen after ultrasonic degasification, the liquid is sealed by vacuum-pumping, and the polymer is then obtained by thermal initiation reaction. The molecularly imprinted polymer is obtained by the steps of elution, desiccation and grinding etc. The molecularly imprinted sulfamethoxazole polymer prepared by the invention has evenly massive structure. Compared with traditional synthetic method, the method is characterized by taking ionic liquid as the pore-forming agent which has excellent catalytic effect for polymer reaction when in the synthesis process. The synthetic polymer has the advantages of excellent dispersity, easy grinding and good molecular recognition properties, which can be used as solid phase extracting agent and packing materials for liquid phase chromatography to realize dispersion, concentration and purification of sulfonamides and resolving the defect of serious impurity interference of the existing common chromatographic detection.
URL: http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_gb&FT=D&date=20080820&CC=CN&NR=101245121A&KC=A