Inventors: Zhang DB, Wu AB, Song SQ
Patent Title: Method of preparing erythromycin molecular engram polymer
Publication date: 2008
Publication number: CN101143910

Abstract: The invention relates to a preparation method of an erythrocin molecularly imprinted polymer, which belongs to the technical field of chemical engineering. According to the molar ratio of 1:2 to 8:20, template molecules, function monomer methacrylic acid and crosslinking agent ethylene glycol dimethacrylate are resolved in pore-foaming agent, which is a mixed solution of methanol and acetonitrile which have a proportion of 1:1 to 2. After azobisisobutyronitrile is added, the temperature of 60 DEG C induces polymerization. Reaction lasts twenty four to forty eight hours. After the reaction, the product is ground and filtered, so that particles with a particle diameter of about 38 Mu m are obtained. The particles are repetitively washed by methanol acetate solution for a few times in order to remove the templates, and after vacuum drying, the erythrocin molecularly imprinted polymer is obtained. The polymer prepared by the invention can be applied to the test of erythrocin residue in environment or in foodstuffs and the removal of the concentration and substrate of trace erythrocin.
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