Inventors: Lam HW, Gong CB
Patent Title: Solvatochromic functional monomer and the use thereof for chemosensing by solvatochromic molecular imprinting
Publication date: 2011
Publication number: US20110003397

Abstract: The present invention relates to a solvatochromic functional monomer having the chemical structure as shown in the accompanying drawing (FIG. 3), and a process for preparing the solvatochromic functional monomer (FIG. 2). The solvatochromic functional monomer can be used for fabrication of molecularly imprinted polymer based (MIP-based) solvatochromic chemosensors. This involves the incorporation of the solvatochromic functional monomer as reporter into the molecularly imprinted polymer. The solvatochromic functional monomers as reporters signal the analyte-to-receptor displacing event within the receptor sites without the need of intermolecular interaction between the analyte and receptor. The invention also relates to a MIP-based solvatochromic chemosensing approach. This involves the combination of solvatochromism and molecular imprinting technique in the chemosensing of target analytes.
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