Inventors: Zheng Z
, Zhao LN
, Wang M
Molecularly imprinted three-dimensionally ordered macroporous sensor and method of forming the same
Publication date: 2011
A molecular imprinted three-dimensionally ordered macroporous (MiTOM) sensor for detecting small organic molecules and a method of forming the same. A target template associated with a number of pores can be formed by vertical deposition of organic polymer particles on a substrate. Active monomers can be added to a solution during an infiltration process of the target template. The monomers associated with ligands can be polymerized around the target template so that the ligands can be stereochemically fixed at precise binding sites associated with the target template. The target template can then be removed in order to form a MiTOM sensor electrode, which includes an inverse opal structure. Additionally, an inverse opal backbone structure can be formed and coated with the layer of target template and active monomers in order to form molecular imprinted active sites on the inverse opal backbone structure after a self-assembly and polymerization process.
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