Inventors: Perollier C
, Naraghi K
, Bayoudh S
Method for producing a radioactive tracer
Publication date: 2011
The present invention relates to a method for preparing a radioactive tracer provided with a radioactive fluorine isotope, including at least the following steps consisting in: i) providing a precursor of the radioactive tracer, comprising at least one leaving group completely or partially formed by a labelling entity, wherein said leaving group can be moved by a fluoride ion; ii) providing a molecularly imprinted polymer dedicated to the molecular recognition of at least the aforementioned labelling entity; iii) exposing the precursor to a radioactive fluoride ion source under conditions suitable for the movement of the leaving group by a radioactive fluoride ion; iv) placing the mixture resulting from step (iii) in contact with the molecularly imprinted polymer under conditions suitable for the recognition of the labelling entity; and v) obtaining a solution containing the radioactive tracer provided with a radioactive isotope of fluorine obtained at the end of step (iii).
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