Inventors: Krozer A, Reimhult K, Lojving B, Malm B, Ye L, Yoshimatsu K
Patent Title: Customized molecularly imprinted polymer (MIP) units
Publication date: 2012
Publication number: US20120045838

Abstract: A method of manufacturing at least one customized MIP unit including: (a) providing at least one MIP unit having a surface including at least one target binding site configured to resemble a target molecule and surface-bound chargeable groups; (b) contacting the MIP unit(s) from the step (a) with at least one template molecule in a first solvent allowing the template molecule(s) to bind to the MIP unit(s); (c) passivating the surface-bound chargeable groups on the MIP unit(s) by adding a passivating agent; and (d) removing the template molecule(s) by washing in a second solvent, wherein the passivating agent binds to the surface of the unit(s) through bonds which remain stable upon washing in the second solvent.
URL: http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120223&DB=EPODOC&locale=en_gb&CC=US&NR=2012045838A1&KC=A1&ND=4