Inventors: Shahgaldian P, Cumbo A, Corvini P
Patent Title: Preparation of a molecular recognition element
Publication date: 2012
Publication number: WO2012034946

Abstract: The present invention relates to a method for preparation of a molecular recognition element (1, 11, 111) comprising the steps of binding a template (4) to a surface of a carrier material (3, 30), providing a recognition material to the surface of the carrier material (3, 30), initiating polymerization of the recognition material on the surface of the carrier material (3, 30), stopping the polymerization of the recognition material on the surface of the carrier material (3, 30), and releasing the template (4) from the surface of the carrier material (3, 30) and the polymerized recognition material (6, 60). The method is characterized in that an aim size of individual imprints (10, 100, 120) is predefined, and the polymerization of the recognition material on the surface of the carrier material (3, 30) is stopped when a size of individual imprints (10, 100, 120) of the polymerized recognition material (6, 60) essentially equals the predefined aim size. This method is readily applicable for preparation of a molecular recognition element al (1, 11, 111) useful as a drug, catalyst, competitive affinity ligand inhibitor, competitor, agonist, antagonist or diagnostic agent.
URL: http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120322&DB=EPODOC&locale=en_gb&CC=WO&NR=2012034946A1&KC=A1&ND=4