Inventors: Hu Q, Sheng N, Wei FD, Xu GH, Cai Z, Du SH, Li F, Zhou XM
Patent Title: Bisphenol A dummy template molecularly imprinted stir bar and preparation method thereof
Publication date: 2012
Publication number: CN102416313

Abstract: The invention relates to a bisphenol A dummy template molecularly imprinted stir bar and a preparation method thereof. The stir bar is a glass bar containing an iron core, wherein the glass bar is coated by a polymer coating; the polymer coating is a bisphenol A dummy template molecularly imprinted polymer; modified silica microspheres with grain size being 400nm are taken as the carriers for synthesizing the imprinted polymer; and biphenyl diphenol is taken as a dummy template molecule. The bisphenol A dummy template molecularly imprinted polymer is prepared by carrying out surface grafting on the surfaces of silica microspheres with grain size being 400nm with vinyltrimethoxysilane to obtain the modified silica microspheres, then subjecting the modified silica microspheres to react with biphenyl diphenol, 4-vinyl pyridine, ethylene glycol dimethacrylate and azodiisobutyronitrile and using a methanol-glacial acetic acid mixed solution to wash off the template molecule. The stir bar and the preparation method have the following beneficial effect that: SiO2 is taken as the carrier for synthesizing the imprinted polymer, thus greatly adding the number of the effective binding sites and improving the sensitivity.
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