Inventors: Mohapatra S, Wang CY
Patent Title: Molecularly imprinted polymers having affinity for natriuretic peptides
Publication date: 2012
Publication number: WO2012138429

Abstract: The present invention concerns molecularly imprinted polymers (MIPs) having an affinity for natriuretic peptides, such as atrial natriuretic peptide (ANP). In some embodiments, the M I P is a nanoparticle (a molecularly imprinted polymeric nanoparticle (MIPNP)). Other aspects of the invention include methods of preparing an MiP having affinity for a natriuretic peptide, methods for binding a natruiretic peptide in vitro or in vivo using an MIP of the invention, methods for interfering with the binding of a natriuretic peptide with its receptor in vivo, methods for reducing inflammation, cell growth, cell differentiation, or a cell proliferation disorder, methods for detecting natriuretic peptides, and devices and kits for sequestering and/or detecting natriuretic peptides.
URL: http://worldwide.espacenet.com/publicationDetails/biblio;jsessionid=7B59B35862E8DD6CC1C00C149B16660F.espacenet_levelx_prod_3?FT=D&date=20121011&DB=EPODOC&locale=en_EP&CC=WO&NR=2012138429A1&KC=A1&ND=1