Inventors: An FQ, Du RK, Gao BJ
Patent Title: Preparation method of new material for separating chiral aspartic acid
Publication date: 2011
Publication number: CN102225989

Abstract: The invention discloses a preparation method of a new material for separating chiral aspartic acid, and solves the problems of difficulty and low efficiency of L-Asp separation currently. The method comprises the following steps of: activation of silica gel particles; chemical bonding of the silica gel particles with a double bond-containing silane coupling agent; chemical grafting of the silica gel particles with polydimethylaminoethyl methacrylate; and preparation of silica gel particle surface molecularly imprinted polymer. The invention adopts silica gel particles as carriers, adopts dimethylaminoethyl methacrylate as a functional macromolecular material grafted on the particles or the particle surfaces, and adopts ether dihalide as a cross-linking agent to prepare the surface imprinted material with high molecular binding speed, strong recognition selectivity, high binding capacity to L-Asp; the surface imprinted material prepared by the invention is suitable for the requirements of industrial production, and has high material utilization rate, low cost, and very good selectivity, recognition and bonding performance to L-Asp molecules.
URL: http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111026&DB=EPODOC&locale=en_EP&CC=CN&NR=102225989A&KC=A&ND=4