Inventors: Yin XY, Luo YM, Jing YF, Zhong YQ
Patent Title: Preparation method and application of codonopsis lactone molecularly imprinted solid phase extraction column
Publication date: 2011
Publication number: CN102174138

Abstract: The invention discloses a preparation method and application of a molecularly imprinted polymer which is used for directly and directionally extracting and separating codonopsis lactone from extraction solution of codonopsis which is a Chinese medicinal herb. The polymer can be used as a filler to be made into a solid-phase extraction column used for extracting and separating codonopsis lactone from the extraction solution of a Chinese medicinal herb.; Compared with a C18 bonded solid-phase extraction column and a silica gel solid-phase extraction column, the codonopsis lactone molecularly imprinted solid phase extraction column has better selectivity to the codonopsis lactone in the extraction solution, has higher capacity of up to 8. 6 mumol/g, is two to three times the capacity of both the C18 bonded solid-phase extraction column silica and the gel solid-phase extraction column, and also has elution rate of 93% higher than the C18 bonded solid-phase extraction column silica and the gel solid-phase extraction column.; The method used for extracting and separating the codonopsis lactone ensures that the prepared product has high purity, is easy to operate and realize industrialization, adopts less solvent, is safer and more environmental friendly and can achieve the purposes of removing impurities, purifying and enriching the codonopsis lactone.
URL: http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110907&DB=EPODOC&locale=en_EP&CC=CN&NR=102174138A&KC=A&ND=4