Inventors: Wei QQ
, Wei TX
, Zhang QW
Surface plasma resonance sensor chip and preparation method thereof
Publication date: 2010
The invention relates to a surface plasma resonance sensor chip and a preparation method thereof, in particular to a photografting molecularly imprinted polymer membrane-based surface plasma resonance sensor chip and a preparation method thereof, and belongs to the field of surface plasma sensor chip preparation. The chip comprises a glass substrate, a gold membrane layer, a unimolecular alkyl chain layer and a molecular imprinted polymer membrane, wherein the gold membrane layer is plated on the glass substrate, the unimolecular alkyl chain layer is self-assembled on the glass substrate, and the molecular imprinted polymer membrane is grafted on the unimolecular alkyl chain layer in turn. The molecular imprinted membrane with nanoscale thickness can be conveniently and quickly prepared on the surface of the gold membrane by the preparation method and has controllable thickness; the growth changes of the molecular imprinted membrane can be dynamically monitored in real time in situ; operation steps are simple and deoxidation and nitrogen protection are not needed; and the matrix type molecular imprinted structural units are easy to prepare on the surface of the gold membrane, each unit can be different template molecules and multi-channel and multi-target molecular detection is realized.
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