Patent 2481

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Inventors: Li F
Patent Title: Acyclovir molecularly imprinted polymer, preparation method and application thereof
Publication date: 2010
Publication number: CN101812158

Abstract: The invention discloses an acyclovir molecularly imprinted polymer, a preparation method and application thereof. The polymer is prepared through the following steps of: (1) dissolving bi-methyl acryloyl acyclovir into an acetonitrile and dimethylsulfoxide solution containing a cross-linking agent and an initiating agent, sealing an obtained mixed solution and then carrying out a polymerization reaction to generate a white powdered polymer, wherein the temperature of the polymerization reaction is 50-70 DEG C, and the reaction time is 12-24h; and (2) heating and extracting the white powdered polymer to remove the template molecule acyclovir, and then extracting by using pure methanol to remove water to obtain the acyclovir molecularly imprinted polymer. The acyclovir molecularly imprinted polymer can be applied to efficiently purifying valcyte intermediates.
URL: http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100825&DB=EPODOC&locale=en_EP&CC=CN&NR=101812158A&KC=A&ND=4

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