Inventors: Li JH, Chen LX, Dong RC
Patent Title: Method for preparing estradiol molecularly imprinted magnetic microsphere
Publication date: 2014
Publication number: CN104140487

Abstract: The invention belongs to the field of materials science and engineering and environmental sciences, and particularly relates to a method for preparing an estradiol molecularly imprinted magnetic microsphere in a controllable living polymerization potful compositing mode. According to the method, a reversible addition-fracture chain transfer controllable living free radical polymerization and precipitation polymerization potful compositing mode is adopted, molecularly imprint with 17 beta estradiol as a template and a sensitive material are combined, and then the estradiol molecularly imprinted magnetic microsphere is obtained. The microsphere obtained through the method is high in adsorption capacity for 17 beta estradiol, has the high-speed dynamic character and the superior recognizing and selecting performance, is separated conveniently and quickly under the action of an applied magnetic field, and is good in reusing performance. According to the method, the character of reversible addition-fracture chain transfer controllable living polymerization is utilized fully, step-by-step feeding potful operation is adopted to prepare the core-shell structure printed microsphere, the surface printing process is effectively simplified, the experimental period is shortened, the recognizing speed is greatly improved, and the printing capacity is increased.
URL: http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20141112&CC=CN&NR=104140487A&KC=A